If you qualify for the study, you will be required to visit a study clinic in your area numerous times over 24 weeks.
The study will be evaluating the efficacy of an investigational study drug for Prurigo Nodularis. Volunteers who qualify to take part in the study may receive compensation for time and travel expenses.
You may be able to take part in the Prurigo Nodularis Studies if you:
All study-related care will be provided by a team of medical professionals.
Prurigo Nodularis is a rare skin condition that causes the formation of hard, itchy lumps referred to as ‘nodules’ on the skin. The itching can be very intense, which can cause scratching that leads to pain and bleeding. This itching is worsened by heat, sweating and irritants such as clothing rubbing on the affected area.
Although scratching is known to cause more nodules to appear, the exact cause is unknown as to why the intense itching and nodules appear in the first place. It is not thought that PN is inherited, however, because conditions such as eczema may contribute to the condition, some instances of PN may be hereditary, which is related to family history and environmental factors, such as the climate which someone lives in.
A diagnosis of Prurigo Nodularis is typically done by a skin biopsy, where it can be seen under a microscope that the nerves in the skin are thickened as a result of the condition. After a diagnosis, further testing may be performed such as blood tests, to ensure there are no other issues related to liver or kidney function.
Although treatments may help relieve the symptoms of Prurigo Nodularis, there is no cure. Topical steroid creams, oral corticosteroids and antihistamines can be effective for some cases in managing the symptoms, as well as habit-reversal therapy that can help assist with resisting the urge to scratch.
The Prurigo Nodularis Studies are investigating a new medication that may help to effectively relieve the symptoms of PN.
A Clinical research study (also called a clinical trial) is a medical study that helps to answer important questions about an investigational drug or device, such as: Does it work, or how effective is it compared to another drug/device?
All medications must be tested in clinical research studies before they can be approved by regulatory authorities for doctors to prescribe to patients. Without people taking part in these studies, we would have no new treatments. The volunteers who participate in clinical research studies play a major role in helping to advance medicine.
If you choose to participate in the Prurigo Nodularis Studies, your case will be followed for about 24 weeks. You will be required to complete approximately 36 study site visits as well as telephone calls. At these visits you will undergo health assessments such as medical questionnaires and a complete physical examination.
All study-related care is provided at no cost to you. You do not need health insurance to participate.
Volunteers who take part in the study may be eligible to receive compensation for their time and travel.
There is no cost to participate in the Prurigo Nodularis Studies. If you qualify, the investigational drug, study-related tests, assessments, and visits will be provided to you at no cost. You will receive study-related care throughout the study from a team of professional doctors and nurses.
Volunteers who take part in the studies may be compensated for their time and travel. Please discuss this with the study team when they contact you.
What happens if I Sign Up? If you sign up, we will match you to a study clinic in your area that is seeking participants or notify you when one becomes available. They will contact you to explain more about the study before you make your decision about participating. You will attend an in-person visit where the study team will help determine if you qualify and if the study is right for you.
If you think you might like to join the Prurigo Nodularis or would like more information, please enter your information below so we can see if you qualify and can contact you about the study.